Inflammatory Bowel Disease in Cats

Chronic cases of diarrhea in cats are a familiarIBD is a term used to describe the inflammation
headache for many veterinarians. Symptoms canof one of the layers in the intestinal wall. This
wax and wane over a period of time, which canswelling of the gut wall may occur with many
complicate the veterinarians assessment of theother intestinal diseases, but when no cause of
response to treatment in some cases. Many,the inflammation is found after doing thorough
though not all of these cats, will havetesting as described above, the condition is
inflammatory bowel disease (IDB). This article willdescribed as idiopathic IBD (essentially, IBD of
focus on how a veterinarian is able to diagnoseunknown cause). IBD is thought to be an
IBD, and what the treatment options are.overreaction to bacteria or dietary ingredients
There are many possible underlying causes whenwithin the gut.
a cat presents with vomiting, diarrhea or weightAre certain types of cats affected more than
loss:others?
1. Parasites (worms)Any age of cat can be affected, and pedigree
2. Viral disease (Coronavirus, Leukaemia virus)breeds may be more commonly affected than
3. Bacteria (Salmonella, Campylobacter)domestic shorthair cats.
4. Protozoa (Giardia, Tritrichomonas)What are the treatment options once IBD has
5. Dietary (food intolerance, food allergy)been diagnosed?
6. Cancer (lymphoma, adenocarcinoma)DIET
7. Inflammatory bowel diseaseMany cats can be managed by diet alone in the
8. Hormonal or metabolic (hyperthyroidism, kidneylong term. Diets can be hypoallergenic, high fiber
failure)or low residue. Sometimes all three of these
9. Drug or toxin inducedtypes of food need to be trialed before the most
10. Motility disorderseffective one is selected. Cats are often resistant
The veterinarian should take a full history fromto dietary trials, and this is the main reason why
the owner, to avoid spending time and money onmany cats are given drugs to treat their IBD, the
unnecessary testing. Factors to be considered arecat will just not eat the specific diet.
age, diet, appetite, worming history, weightHypoallergenic foods usually contain a new protein
change and the nature of the vomiting or diarrhea.source that the cat has not encountered before
It is important to differentiate vomiting fromsuch as capelin & tapioca, duck, venison or
regurgitation, which is usually an esophagealhydrolyzed protein. Diets high in fiber are
problem, and to differentiate small intestinalrecommended for colonic disease.
diarrhea from large intestinal diarrhea by theDRUGS
frequency and consistency of the feces.Drugs are a last resort, if the cat is still showing
The veterinarian will then carry out a full clinicalsymptoms despite various food trials or if the cat
examination, before embarking on a basicrefuses to eat the prescription diet.
approach to the diagnosis as follows:Options are:
1. Blood and urine tests to rule out disease1. Anti inflammatory or immunosuppressive drugs
elsewhere in the body which has a knock onPrednisolone, a corticosteroid given at 2-4mg/kg,
effect on the gastrointestinal tract.is the most effective drug.
2. Bacterial culture of the feces to rule out2. Budesonide
Salmonella & CampylobacterThis is also a steroid, with fewer side effects on
3. Parasite check on the feces to rule out wormsthe rest of the body but it is unlicensed.
4. Xrays to rule out an obstruction by a foreign3. Chlorambucil
body or a tumorSometimes given in addition to a steroid if the
5. Ultrasound examination of the abdomen tosteroid alone working.
measure gut wall thickness4. Metronidazole
6. Bland prescription diet for 4-6 weeks (e.g. Hills ZThis reduces the number of bacteria in the gut,
D, Royal Canin Sensitivity Control)so theoretically will reduce the triggering factor for
7. Intestinal biopsies via endoscopy or surgery.the inflammation.
IBD is a diagnosis of exclusion, so all of the5. Cyclosporine
differentials previously mentioned must be ruledNormally used in dogs, this modifies the immune
out in order to make the diagnosis.system. It has only been tried in a small number
What is inflammatory bowel disease?of cats, with mixed results.